(CDMF NO.: F20209990126)
Package: 0.5kg/bottle*12 /carton; 0.8kg/bottle*24 /carton;
R = hydrocarbon mixture from n-C18H17 to n-C18H37
mainly n-C12H25, n-C14H29, n-C16H33
White waxy solid or yellow colloid; its aqueous solution is neutral or weakly alkaline, and a large amount of foam is generated when shaking. Easily soluble in water or ethanol, slightly soluble in ether.
Quality Standard: CHP 2020; USP40-NF35; EP9.0
C12 NLT 40.0%; C14 NLT 20.0%; C12+C14 NLT 70.0%
It is a cationic surfactant of the quaternary ammonium salts.
As preservatives, widely used in ophthalmic preparations, but also in nasal and ear preparations, small volume injections and cosmetics.
|Ophthalmic preparation||0.01% -0.02%||Lysozyme eye lotion|
|Nasal and ear preparation||0.002% -0.02%|
|Small volume injection||0.01%||Hydrocortisone phosphate injection|
This product is incompatible with aluminum, anionic surfactants, citrate, cotton, fluorescein, hydrogen peroxide, hypromellose, iodide, kaolin, lanolin, nitrate, and high-concentration nonionic surfactants, permanganic acid, protein, salicylate, silver salt, soap, sulfa drugs, zinc oxide, zinc sulfate, some rubber mixtures and some plastic mixtures.
This dilute solution is usually non-irritating, non-allergenic and easily tolerated in transdermal and mucosal preparations.
It has hygroscopicity. Light, air and metal affect its stability.
Stored in sealed container in a cool, dry and dark place, and avoid contact with metal.