Glyceryl Dibehenate
(CDMF NO.: F20209990110)
Definition: Glyceryl dibehenate NF38 /CP2020 ；Glycerol dibehenate EP10.0
CAS No.：30233-64-8/ 18641-57-1/77538-19-3
Package: 1kg/bag, 5kg/carton, 20kg/drum
Bag in cardboard drum 20 kg (polyethylene bag).
Sample available upon request.
Appearance: White or off-white powder or hard wax block; it has a slight odor.
Soluble in chloroform and almost insoluble in water or ethanol.
Origin of the raw materials
The product is manufactured from raw materials of strictly vegetable origin.
Description
– CAS: 77538-19-3 (or 91052-55-0) (or 30233-64-8) (or 94201-62-4)
– EINECS: 278-717-5 (or 293-216-1) (or 250-097-0) (or 303-650-6)
Quality Standard: ChP2020; USP43-NF38; EP10.0; GB1886.65-2015
Application:
*As a binder and lubricant for tablets and capsules
*As a matrix material or coating material for sustained-release preparations
*As a thickener for silicone gelling agents and emulsions
*As a taste masking agent
*Used as emulsifier in food.
*Used in daily chemical products such as facial cleanser, toner, shampoo, toothpaste.
| Application | Dosage/ % | Examples |
| Sustained&controlled release material | 10.0~ 50.0 | Loratadine and Pseudoephedrine Sulfate Sustained Release Tablets |
| Fat-soluble coating material | >10.0 | |
| Lubricants for tablets, etc | 1.0-3.0 | Captopril Tablets |
| Taste-masking agent | Amoxicillin Dry Suspension | |
| Adhesives for tablets, etc | 1.0-3.0 | |
| Thickeners for gels, emulsions, etc | 1.0-15.0 |
Benefits:
1.As a sustained release skeleton material:
Suitable for a wide range of tabletting process: direct tabletting, wet granulation, dry granulation and hot melt granulation;
PH-independent drug release;
Burst-free drug release related to ethanol;
Drug release through diffusion mechanism to avoid burst effect;
Without digestion and high physiological tolerance.
2. As a lubricant:
No effect on disintegration time and drug release;
Improve compressibility in tablet and capsule production;
Do not interfere with drug testing;
Do not reduce tablet hardness;
Acid drugs can use it.
Safety: Generally considered non-toxic and non-irritating.
Storage: Preserve in tight containers at a temperature not higher than 35°