Glycerol Distearate
(CDE REGISTRATION NO.: F2024000316)
Name: Glycerol Distearate
Other Name: Glyceryl Distearate
CAS No.: 1323-83-7
Packaging: 1kg/bag/carton; 5kg/bag/carton; 20kg/bag/drum
Appearance: Hard, waxy mass or powder, or white or almost white, unctuous flakes.
Practically insoluble in water, soluble in methylene chloride, partly soluble in hot ethanol (96%).
Quality Standard: USP2024, EP11.0
Specifications:
| Alpha code | Specifications |
| AG5601 | Type I: Stearic acid: 40.0 per cent to 60.0 per centSum of the contents of palmitic and stearic acids: minimum 90.0 per cent |
| AG5602 | Type II: Stearic acid: 60.0 per cent to 80.0 per centSum of the contents of palmitic and stearic acids: minimum 90.0 per cent |
| AG5603 | Type III : Stearic acid: 80.0 per cent to 99.0 per centSum of the contents of palmitic and stearic acids: minimum 96.0 per cent |
Features:
Glycerol Distearate is a mixture of diglycerides, primarily glyceryl distearate, along with varying amounts of monoglycerides and triglycerides. It contains 8.0% to 22.0% monoglycerides, 40.0% to 60.0% diglycerides, and 25.0% to 35.0% triglycerides.
Applications:
| Dosage form | Application | Dosage |
| Granules, dry suspension | Taste masking materials | 2-6% |
| Tablet | Lubricants | 1-4% |
| Sustained-release preparations | Dissolving skeleton material | 10-20% |
| Ointment | Thickening agent, improving spreadability | 2-10% |
| Oral Liquid dosage form | Thickening agent | 0.5-3% |
Advantages:
■ It has been applied to the new hot melt granulation method to produce granules and tablets
■ It is widely used in cosmetics, food, oral and topical preparations, etc. It is generally considered non-toxic and non-irritating to the skin and mucous membranes
■Excellent emulsifying and thickening properties, suitable for various formulations.
Incompatibilities
■Incompatible with strong oxidizing agents (e.g., potassium chlorate, hydrogen peroxide).
■May react with certain metal ions (e.g., aluminum, copper); coexistence should be avoided.
Safety
■According to available data, Glycerol Distearate is considered a low-toxicity substance.
■Safe for use at recommended levels; no significant irritation or allergic reactions have been reported.
■Follow appropriate safety procedures to avoid inhalation of dust and direct contact.
Storage:: Preserve in tight containers. No storage requirements are specified.(USP2024)
Under nitrogen, in an airtight container.(EP11.0)